Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Reactivity: Rat Format: Unconjugated, Concentrated. The protein encoded by this gene is the more abundant major subunit. ASGPR antibody LS-C204173 is an unconjugated mouse monoclonal antibody to rat ASGPR (ASGR1). Anti-Asialoglycoprotein Receptor 1/2/ASGR1/ASGR2 Antibody (E-1) has 1 citations in a variety of scientific publications. Find the ASGR1 antibody that fits your needs. These antibodies have been verified by Relative Expression to confirm specificity to ASGR1. Our ASGR1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. These antibodies target ASGR1 in Human, Mouse, Rat and Porcine samples. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. Species Reactivity: Human, Mouse, Rat Applications: Flow Cytometry, Immunohistochemistry (Paraffin). These antibodies target ASGR1 in Human, Mouse, Rat and Porcine samples. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody. Proteins were transferred to a membrane and probed with a ASGR1 Polyclonal Antibody (Product PA5-32030) at a dilution of 1:3000. This gene encodes a subunit of the asialoglycoprotein receptor. ASGR1 Antibody, 11739-1-AP, from Proteintech. ASGR1 Mouse Anti-ASGR1 Recombinant Antibody (clone 27F1) (MOB-2957z) Derivation: Mouse Species Reactivity: Human Type: Mouse IgG1 Application: WB, ELISA. Western blot analysis of ASGR1 was performed by separating 50 g of mouse tissue extract by 10 SDS-PAGE. Molecular Function:protein binding protein homodimerization activity metal ion binding asialoglycoprotein receptor activity carbohydrate bindingīiological Process: receptor-mediated endocytosis cellular response to extracellular stimulus The receptor then returns to the cell membrane surface.Ĭhromosomal Location of Human Ortholog: 17p13.2Ĭellular Component: integral to plasma membrane extracellular region

After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor recognizes terminal galactose and N-acetylgalactosamine units. Asialoglycoprotein receptor 1 ASGR1 ASGPR CLEC4H1 Hs.12056 ĪSGR1: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.

Asgr1 antibody reactivity mouse